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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EPB41L5
All Species:
7.27
Human Site:
T685
Identified Species:
12.31
UniProt:
Q9HCM4
Number Species:
13
Phosphosite Substitution
Charge Score:
0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9HCM4
NP_065960.2
733
81856
T685
A
G
C
E
M
L
L
T
G
K
E
G
H
G
N
Chimpanzee
Pan troglodytes
XP_001157953
733
81845
T685
A
G
C
E
M
L
L
T
G
K
E
G
H
G
N
Rhesus Macaque
Macaca mulatta
XP_001088764
726
81122
G679
G
C
E
M
L
L
A
G
K
E
G
H
G
N
K
Dog
Lupus familis
XP_532028
914
101864
S773
S
E
G
K
G
Q
L
S
P
G
A
K
S
P
S
Cat
Felis silvestris
Mouse
Mus musculus
Q8BGS1
731
81617
G684
G
Y
G
A
S
L
A
G
T
D
E
C
S
Q
K
Rat
Rattus norvegicus
Q5FVG2
731
81700
G684
G
Y
G
V
S
L
T
G
T
E
G
C
N
Q
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509941
820
90648
G685
L
G
P
E
E
S
L
G
R
K
G
N
Q
S
D
Chicken
Gallus gallus
XP_422083
502
57358
G457
A
A
D
R
C
Q
R
G
G
S
P
W
D
A
R
Frog
Xenopus laevis
NP_001080234
498
57093
S453
G
V
T
E
D
A
R
S
G
R
R
Q
Q
A
A
Zebra Danio
Brachydanio rerio
O57457
619
70690
Q574
P
Y
K
K
V
E
T
Q
G
D
P
I
K
I
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_650291
972
105216
E862
A
S
G
S
I
T
A
E
T
A
A
K
P
A
G
Honey Bee
Apis mellifera
XP_623974
809
90976
L764
I
Q
T
T
T
T
T
L
T
H
K
D
D
N
S
Nematode Worm
Caenorhab. elegans
P28191
1026
115075
D886
L
M
I
K
C
I
K
D
K
Q
T
T
N
C
C
Sea Urchin
Strong. purpuratus
XP_788387
843
92835
L687
V
S
N
H
E
A
A
L
M
Q
C
G
K
S
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.7
95.2
39.8
N.A.
83.9
83.6
N.A.
56.5
56.6
54.4
28.5
N.A.
36.8
38.9
24.3
39.1
Protein Similarity:
100
99.3
96.3
52.1
N.A.
89.2
88.4
N.A.
65.1
62.2
60.9
44.7
N.A.
51.8
53.1
40.1
56.7
P-Site Identity:
100
100
6.6
6.6
N.A.
13.3
6.6
N.A.
26.6
13.3
13.3
6.6
N.A.
6.6
0
0
6.6
P-Site Similarity:
100
100
20
33.3
N.A.
13.3
20
N.A.
33.3
13.3
26.6
20
N.A.
13.3
13.3
26.6
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
29
8
0
8
0
15
29
0
0
8
15
0
0
22
8
% A
% Cys:
0
8
15
0
15
0
0
0
0
0
8
15
0
8
8
% C
% Asp:
0
0
8
0
8
0
0
8
0
15
0
8
15
0
8
% D
% Glu:
0
8
8
29
15
8
0
8
0
15
22
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
29
22
29
0
8
0
0
36
36
8
22
22
8
15
8
% G
% His:
0
0
0
8
0
0
0
0
0
8
0
8
15
0
0
% H
% Ile:
8
0
8
0
8
8
0
0
0
0
0
8
0
8
0
% I
% Lys:
0
0
8
22
0
0
8
0
15
22
8
15
15
0
29
% K
% Leu:
15
0
0
0
8
36
29
15
0
0
0
0
0
0
0
% L
% Met:
0
8
0
8
15
0
0
0
8
0
0
0
0
0
0
% M
% Asn:
0
0
8
0
0
0
0
0
0
0
0
8
15
15
15
% N
% Pro:
8
0
8
0
0
0
0
0
8
0
15
0
8
8
0
% P
% Gln:
0
8
0
0
0
15
0
8
0
15
0
8
15
15
0
% Q
% Arg:
0
0
0
8
0
0
15
0
8
8
8
0
0
0
15
% R
% Ser:
8
15
0
8
15
8
0
15
0
8
0
0
15
15
15
% S
% Thr:
0
0
15
8
8
15
22
15
29
0
8
8
0
0
0
% T
% Val:
8
8
0
8
8
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% W
% Tyr:
0
22
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _